HTTP > Advanced Threat Protection > Policies and then open the Virus Scan Rule tab
after Adding or edit an existing policy
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All scannable files: For maximum security, Trend Micro recommends that you scan all scannable file types.MORE>>
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IntelliScan: Choose this option to scan only those files types known to be susceptible to viruses.MORE>>
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Specific file extensions: This option is potentially the least secure, but does offer the fastest scanning
performance.
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MIME content-type to skip: You can prevent IWSVA from scanning certain MIME content types. This may be necessary,
for example, if scanning interferes with the delivery of real-time streaming content
such as RealPlayer or the Microsoft download manager.